Two novel single nucleotide polymorphisms (SNPs) of the CYP2D6 gene in Japanese individuals.

نویسندگان

  • Aiko Ebisawa
  • Masahiro Hiratsuka
  • Kanako Sakuyama
  • Yumiko Konno
  • Takamitsu Sasaki
  • Michinao Mizugaki
چکیده

We analyzed all the exons and exon-intron junctions of the CYP2D6 gene from 286 Japanese individuals. We detected two novel single nucleotide polymorphisms (SNPs) 2556C>T in exon 5 (Thr261Ile) and 3835A>C in exon 8 (Lys404Gln). Both these SNPs showed a frequency of 0.002.

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عنوان ژورنال:
  • Drug metabolism and pharmacokinetics

دوره 20 4  شماره 

صفحات  -

تاریخ انتشار 2005